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Nipple Discharges, Causes, and Indications

Blood-stained and serosanguinous discharge

Blood-stained and serosanguinous discharge

Nipple discharges are among women’s top concerns, most especially when they are not pregnant or breastfeeding. Women wonder what causes such discharges, and why it’s happening. This would oftentimes make them feel anxious. But is this really a major concern, or something that should be taken lightly?

Before jumping into conclusions, let’s know what are nipple discharges, what causes it, and what it indicates.

According to experts, nipple discharges refers to any fluid that seeps out of the nipple in a nonlactating woman. Nonmilk discharges may also come out of the breasts through the same nipple openings that carry milk.

One or both breasts may produce a nipple discharge, either spontaneously or when squeezed. A nipple discharge may look milky, or it may be yellow, green, brown or bloody. The consistency of nipple discharge varies from thick and sticky to thin and watery.

While breast milk is expected in pregnancy and after child birth, other secretions from the breast may also occur in women of any age. Young women may experience nipple discharge without any cause for concern but persistent discharge in older women may be a sign of an underlying condition. And also, a nipple discharge in a man, under any circumstances, is problematic and should be investigated.

Secretions from the breast usually occur from the nipple and nipple discharge should be differentiated from fluids secreted through a breast fistula. A breast or mammary duct fistula is an abnormal passage that forms between a mammary duct in the breast to the surface of the skin, usually near the areola. While a mammary fistula is not very common, it may occur after a prolonged infection and the presence of a fistula should not be considered as nipple discharge. A breast fistula requires further investigation and appropriate treatment.

Types of Nipple Discharge

There are different types of nipple discharge and the type of breast secretion may be an indication of the cause of the discharge.

  • Milky discharge may be breast milk production even in women who are not pregnant or breast feeding and is often due to elevated hormonal levels, specifically prolactin.
  • Clear discharge and sticky discharge may be a sign of inflammation or infection.
  • Bloody discharge may be a sign of severe trauma, infection or cancer.
  • Mucus that is yellow or brown and may be mixed with blood could be due to severe infection, especially if accompanied by breast pain.

Evaluating the type of nipple discharge is not usually sufficient to make a conclusive diagnosis. The presence of other signs and symptoms as well as thorough diagnostic investigation by a medical practitioner should determine the underlying cause of the breast discharge.

Signs and Symptoms of Nipple Discharge

Nipple discharge may occur on its own with no other sign or symptoms or may be accompanied by other symptoms which is indicative of certain conditions.

  • Nipple discharge may occur from both breasts (bilateral) or one breast (unilateral)
  • Breast tenderness or breast pain
  • Swollen breasts or breast lumps
  • Fever
  • Irregular menstrual cycle

Causes of Nipple Discharge

In most cases, breast discharge is not a cause for concern but any persistent discharge associated with other changes requires investigation.

Nipple discharge may be related or caused by:

  • Galactorrhea is breast milk production in women who are not pregnant or nursing and is often due to elevated prolactin levels (hyperprolactinemia). Hyperprolactinemia may occur as a result of many conditions including:
    • 1. Stimulation of the breasts
    • 2. Pregnancy
    • 3. Stress
    • 4. Injury to the breast
    • 5. Sexual intercourse.
    • 6. Pituitary disorders
    • 7. Thyroid disorders particularly hypothyroidism
    • 8. Kidney or liver failure
    • 9. Certain drugs like oral contraceptives, antidepressants or antihypertensive drugs.
  • Breast abscess or breast infection due to bacterial, viral or fungal causes is usually accompanied by breast pain, tenderness, redness of the skin with a white to yellow discharge. A painful breast lump may be felt in the case of an abscess. Infections of the breast are usually one sided and may also cause breast swelling.
  • Benign breast disorders:
    • 1. Intraductal papilloma is a small benign tumor of the milk ducts in the breast. It is the most common cause of nipple discharge and usually affects only one breast. The secretion may be bloody or a clear discharge may be noted.
    • 2. Fibrocystic breast disease (FBD) is the most common cause of breast lumps in women, particularly older women. It may affect one or both breasts and the presence of multiple small lumps may be noticed along with breast tenderness.
    • 3. Mammary duct ectasia is the blockage of the milk duct and may affect one breast or both sides. Blockage of the duct often occurs as a result of inflammation due to hormonal changes and may be prone to bacterial infections. Smoking is a predisposing cause for mammary duct ectasia. The nipple discharge in mammary ectasia may vary in color and consistency.
  • Breast cancer, usually intraductal carcinoma, may cause a bloody breast discharge. A breast lump is usually present and swollen lymph nodes (lymphadenopathy) may be noticed.
  • Hormonal disorders affecting the female sex hormones which may occur in perimenopause, premature ovarian failure and polycystic ovarian syndrome. Changes in the menstrual cycle are usually evident, with irregular menses, sudden cessation of periods or changes in menstrual flow. Infertility may also accompany these hormonal disorders.
  • Gynecomastia is the enlargement of the male breast which may be normal during puberty. Persistent enlargement with breast tenderness and/or nipple discharge should be investigated although breast secretions in gynecomastia is not common.

Diagnosis of Breast Discharge

While nipple discharge may occur frequently in women who are not pregnant or breastfeeding, persistent breast secretions should be investigated. Persistent breast discharge is of particular concern in women over 40 years of age, where the discharge is from only one breast, bloody discharge with the presence of breast lumps.

After physical examination and a case history, the medical doctor may consider a mammogram, fine needle aspiration and cytology. If the prolactin levels are elevated, further blood tests may be conducted to evaluate the functioning of the thyroid gland, particularly by testing the thyroid stimulating hormone (TSH).

If you are using any hormone replacement therapy or related drugs for menopause, as contraception or for infertility, the medical doctor may discontinue or change the drugs if the breast discharge is severe and accompanied by other symptoms like breast swelling, tenderness or pain.

Women experiencing nipple discharge with a personal or family history of recurrent breast lumps, even benign lumps. should undergo extensive investigation to exclude breast cancer.


1. “Merck, Nipple Discharge”

2. “National Cancer Institue, Intraductal Carcinoma”

3. “Healthtype.com, Causes of Breast Secretion, Nipple Discharge”

4. “Wrongdiagnosis, Common causes of Nipple Discharge”

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3 Responses to “Nipple Discharges, Causes, and Indications”

  • Venita Holaway says:

    Breastfeeding has a variety of health benefits for both the mother and the infant. The World Heath Organization has a global strategy to encourage it, and Salma Hayek famously breastfed a baby in Africa.

  • S.Mishra says:

    Dear Sir/Madam
    Can u pls tell me why yellow liquids flow from women nipple.Is this a cause of breast cancer

  • admin says:

    There are a variety of causes that may cause a yellowish nipple discharge.

    Of the benign conditions that cause suspicious nipple discharge, approximately half is due to papilloma and the other half is a mixture of benign conditions such as fibrocystic conditions (i.e., lumpy) or duct ectasia (widening and hardening of the duct due to age or damage). For example, women with fibrocystic breasts may experience clear, yellow or light green discharge. Most opalescent discharge is due to duct ectasia or cyst.

    However, Opalescent discharge that is yellow or green in color can also be normal.

    May I know if there are accompanying breast pain? If so, you may need to consult a physician or gynecologist.

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